Drug Therapy
نویسندگان
چکیده
INDIAN PEDIATRICS 1161 VOLUME 42__NOVEMBER 17, 2005 Nitazoxanide (NTZ) is a novel broadspectrum antiparasitic agent originally discovered in 1980s by J.F. Rossignol. Nitazoxanide is effective in broad range of parasitic and protozoal infections including Giardia lamblia, Entamoeba histolytica, Cryptosporidium spp., Ascaris lumbricoides, Hymenolepis nana and Taenia solium/saginata. In combination, these are responsible for 44% of diarrhea and wide variety of symptomatology among children(1). This drug has been approved by US FDA (in Nov 2002) as well as by Drug controller general of India (DCGI) (in June 2004), for treatment of diarrhea caused by Cryptosporidium parvum and Giardia lamblia, in children 1-11 years of age(2,3).
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